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IRF News

Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

DNA prime–recombinant adenovirus type 5 boost (DNA/rAd5) vaccine regimen in persons at increased risk for HIV-1 infection in the United States backfired and was stopped because the “vaccination regime” increased the risk of getting “iHIV-infected”.

Source and details:
http://www.nejm.org/doi/full/10.1056/NEJMoa1310566?query=TOC